Article
Differential Effect of Positive End-Expiratory Pressure Strategies in Patients With ARDS: A Bayesian Analysis of Clinical Subphenotypes.
Chest - 1 Oct 2024
Siuba Matthew T, Bulgarelli Lucas, Duggal Abhijit, Cavalcanti Alexandre B, Zampieri Fernando G, Rey Diego Ariel, Lucena Wellington Dos Reis, Maia Israel S, Paisani Denise M, Laranjeira Ligia N, Neto Ary Serpa, Deliberato Rodrigo Octávio
Abstract excerpt
BACKGROUND: ARDS is a heterogeneous condition with two subphenotypes identified by different methodologies. Our group similarly identified two ARDS subphenotypes using nine routinely available clinical variables. However, whether these are associated with differential response to treatment has yet to be explored. RESEARCH QUESTION: Are there differential responses to positive end-expiratory pressure (PEEP)...
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