Article
Effects of inflammatory phenotypes in acute respiratory distress syndrome on mortality and partitioning of lung and chest wall mechanics in patients in the USA and Canada: a retrospective cohort study.
The Lancet. Respiratory medicine - 1 Jul 2026
Pensier Joris, Fosset Maxime, Paschold Béla-Simon, von Wedel Dario, Sharif Massoud, Braeuer Ben L P, Sahli Sebastian D, Novack Victor, Goodspeed Valerie, Sarge Todd, Jung Boris, Amato Marcelo B P, Sinha Pratik, Talmor Daniel, Schaefer Maximilian S, Baedorf-Kassis Elias
Abstract excerpt
BACKGROUND: Inflammatory phenotypes of acute respiratory distress syndrome (ARDS) predict outcomes and can respond differently to treatment strategies. We aimed to establish whether these phenotypes differ in respiratory mechanics and in response to lung-protective ventilation strategies. METHODS: In this retrospective cohort study, data from two cohorts were harmonised. Patients with moderate-to-severe ARDS with...
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