Article
Acute Respiratory Distress Syndrome Subphenotypes Respond Differently to Randomized Fluid Management Strategy.
American journal of respiratory and critical care medicine - 1 Feb 2017
Famous Katie R, Delucchi Kevin, Ware Lorraine B, Kangelaris Kirsten N, Liu Kathleen D, Thompson B Taylor, Calfee Carolyn S
Abstract excerpt
RATIONALE: We previously identified two acute respiratory distress syndrome (ARDS) subphenotypes in two separate randomized controlled trials with differential response to positive end-expiratory pressure. OBJECTIVES: To identify these subphenotypes in a third ARDS cohort, to test whether subphenotypes respond differently to fluid management strategy, and to develop a practical model for subphenotype...
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