Article
Interleukin-1 gene polymorphisms and toxoplasmic retinochoroiditis.
Molecular vision - 1 Jan 2008
Cordeiro Cynthia A, Moreira Paula R, Costa Germano C, Dutra Walderez O, Campos Wesley R, Oréfice Fernando, Teixeira Antônio L
Abstract excerpt
PURPOSE: It has been proposed that cytokine gene polymorphisms can predispose individuals to disease by enhancing inflammatory processes. Considering the relevance of interleukin-1 (IL-1) in the pathogenesis of toxoplasmic retinochoroiditis (TR), we investigated whether IL1A -889 C/T and IL1B +3954C/T promoter polymorphisms are associated with TR in humans. METHODS: We performed a cross-sectional study that...
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