Article
RAS/RAF mutations and microsatellite instability status in primary colorectal cancers according to HER2 amplification.
Scientific reports - 19 May 2024
Lee Sun Mi, Oh Hyunjoo
Abstract excerpt
HER2 amplification-associated molecular alterations and clinicopathologic features in colorectal cancers (CRCs) have not been well established. In this study, we assessed the prevalence of HER2 amplification and microsatellite instability (MSI) status of 992 patients with primary CRC. In addition...
Topics
- Humans
- Microsatellite Instability
- Colorectal Neoplasms
- Female
- Receptor, ErbB-2
- Male
- Middle Aged
- Mutation
- Aged
- Gene Amplification
- Adult
- Aged, 80 and over
- Proto-Oncogene Proteins B-raf
- Proto-Oncogene Proteins p21(ras)
- High-Throughput Nucleotide Sequencing
- ras Proteins