Article
Extracorporeal membrane oxygenation aggravates platelet glycoprotein V shedding and δ-granule deficiency in COVID-19-associated acute respiratory distress syndrome.
Journal of thrombosis and haemostasis : JTH - 1 Aug 2024
Herrmann Johannes, Weiss Lukas J, Just Bastian, Mott Kristina, Drayss Maria, Kleiss Judith, Riesner Jonathan, Notz Quirin, Röder Daniel, Leyh Rainer, Beck Sarah, Weismann Dirk, Nieswandt Bernhard, Lotz Christopher, Meybohm Patrick, Schulze Harald
Abstract excerpt
BACKGROUND: Extracorporeal membrane oxygenation (ECMO) is a lifesaving therapy in patients with acute respiratory distress syndrome (ARDS). Hemostatic complications are frequently observed in patients on ECMO and limit the success of this therapy. Platelets are key mediators of hemostasis enabling activation, aggregation, and thrombus formation by coming in contact with exposed matrix proteins via their surface...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
