Article

Severity-stratified and longitudinal analysis of VWF/ADAMTS13 imbalance, altered fibrin crosslinking and inhibition of fibrinolysis as contributors to COVID-19 coagulopathy

2020-08-21

Abstract excerpt

<h4>Background</h4> Early clinical reports have suggested that the prevalence of thrombotic complications in the pathogenesis of COVID-19 may be as high as 30% in intensive care unit (ICU)-admitted patients and could be a major factor contributing to mortality. However, mechanisms underlying COVID-19-associated thrombo-coagulopathy, and its impact on patient morbidity and mortality, are still poorly understood. <h...

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Literature Corpus work: b8df991c-abd3-5ae1-a95e-e6adba8714d1
DOI: 10.1101/2020.08.18.20159608

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