Article

COVID-19 Pathophysiology: Are Platelets and Serotonin Hiding in Plain Sight?

2021-03-18

Abstract excerpt

Established evidence suggests that in ARDS, platelets may exhibit a dysregulated state that exacerbates lung injury. We review evidence that suggests this platelet-mediated lung injury, while present in ARDS in general, is amplified in COVID-19 ARDS in particular. Driven by a quantifiably higher degree of platelet activation and ensuing platelet serotonin liberation into plasma compared to ARDS of other etiologies...

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Literature Corpus work: 759252a2-a640-5033-8ca4-9c7ccc0bbf6d
DOI: 10.2139/ssrn.3800402

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