Article
COVID-19 induces a hyperactive phenotype in circulating platelets.
PLoS biology - 1 Feb 2021
Comer Shane P, Cullivan Sarah, Szklanna Paulina B, Weiss Luisa, Cullen Steven, Kelliher Sarah, Smolenski Albert, Murphy Claire, Altaie Haidar, Curran John, O'Reilly Katherine, Cotter Aoife G, Marsh Brian, Gaine Sean, Mallon Patrick, McCullagh Brian, Moran Niamh, Ní Áinle Fionnuala, Kevane Barry, Maguire Patricia B
Abstract excerpt
Coronavirus Disease 2019 (COVID-19), caused by the novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has affected over 30 million globally to date. Although high rates of venous thromboembolism and evidence of COVID-19-induced endothelial dysfunction have been reported, the precise aetiology of the increased thrombotic risk associated with COVID-19 infection remains to be fully elucidated....
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