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Alterations in platelet proteome signature and impaired platelet integrin α <sub>IIb</sub> β <sub>3</sub> activation in patients with COVID-19

2022-10-12

Abstract excerpt

<h4>Background</h4> Patients with coronavirus disease-19 (COVID-19) are at increased risk of thrombosis, which is associated with altered platelet function and coagulopathy, contributing to excess mortality. <h4>Objectives</h4> We aimed to characterise the mechanism of altered platelet function in COVID-19 patients. <h4>Methods</h4> The platelet proteome, platelet functional responses and platelet-neutrophil ag...

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Literature Corpus work
516c4ec6-4b74-5f88-ae77-213e81eeb6ce
DOI
10.1101/2022.10.12.511145
Open publication

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Alterations in platelet proteome signature and impaired platelet integrin α <sub>IIb</sub> β <sub>3</sub> activation in patients with COVID-19DOI 10.1101/2022.10.12.511145
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