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Senescence of endothelial cells promotes phenotypic changes in adventitial fibroblasts: possible implications for vascular aging

14 May 2024

Abstract excerpt

Aging is the most important risk factor for the development of cardiovascular diseases. Senescent cells release plethora of factors commonly known as the senescence-associated secretory phenotype, which can modulate the normal function of the vascular wall. It is currently not well understood if and how endothelial cell senescence can affect adventitial niche. The aim of this study was to characterize oxidative...

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PMID: 38743322
DOI: 10.1007/s11010-024-05028-7

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