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Factors and Pathways Modulating Endothelial Cell Senescence in Vascular Aging

4 Sept 2022

Abstract excerpt

Aging causes a progressive decline in the structure and function of organs. With advancing age, an accumulation of senescent endothelial cells (ECs) contributes to the risk of developing vascular dysfunction and cardiovascular diseases, including hypertension, diabetes, atherosclerosis, and neurodegeneration. Senescent ECs undergo phenotypic changes that alter the pattern of expressed proteins, as well as their...

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PMID: 36077539
DOI: 10.3390/ijms231710135

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