Article
Cellular Senescence and Vascular Disease: Novel Routes to Better Understanding and Therapy.
The Canadian journal of cardiology - 1 May 2016
Yin Hao, Pickering J Geoffrey
Abstract excerpt
Cellular senescence is a definable fate of cells within aging, diseased, and remodelling tissues. The traditional hallmark of cellular senescence is permanent cell cycle arrest but the senescent state is also accompanied by secretion of proteins that can reinforce the senescent phenotype and adversely affect the local tissue environment. Assessment for cellular markers of senescence has revealed the existence of...
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