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Article

CYB561 supports the neuroendocrine phenotype in castration-resistant prostate cancer.

PloS one - 1 Jan 2024

Azur Romie Angelo G, Olarte Kevin Christian V, Ybañez Weand S, Ocampo Alessandria Maeve M, Bagamasbad Pia D

Abstract excerpt

Castration-resistant prostate cancer (CRPC) is associated with resistance to androgen deprivation therapy, and an increase in the population of neuroendocrine (NE) differentiated cells. It is hypothesized that NE differentiated cells secrete neuropeptides that support androgen-independent tumor growth and induce aggressiveness of adjacent proliferating tumor cells through a paracrine mechanism. The cytochrome...

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Share to Cell Differentiation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Prostatic Neoplasms, Castration-Resistant

Source

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Identifiers

PMID: 38739593
DOI: 10.1371/journal.pone.0300413
PMCID: PMC11090301

Genes

CYB561
PC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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