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Genotyping of RB1 status identifies two distinct subtypes in EGFR ‐mutant lung cancers with SCLC transformation

1 May 2024

Abstract excerpt

In this study, we investigate the significant yet underexplored clinical and molecular heterogeneity in epidermal growth factor receptor (EGFR)-mutant lung cancers transformed into small cell lung cancer (SCLC). Our work addresses a crucial unmet need in understanding the molecular underpinnings of this transformation and introduces a novel predictive model for assessing the transformation hazards in high-risk...

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PMID: 38736106
DOI: 10.1002/ctm2.1683

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