Article
Sensitivity to 6-n-propylthiouracil is associated with gustin (carbonic anhydrase VI) gene polymorphism, salivary zinc, and body mass index in humans.
The American journal of clinical nutrition - 1 Sept 2010
Padiglia Alessandra, Zonza Andrea, Atzori Elena, Chillotti Caterina, Calò Carla, Tepper Beverly J, Barbarossa Iole Tomassini
Abstract excerpt
BACKGROUND: The individual ability to taste 6-n-propylthiouracil (PROP) may be correlated with body mass index (BMI) and differences in the salivary proteins involved in taste function, such as the zinc-dependent enzyme gustin, which is a trophic factor of taste buds. OBJECTIVE: We investigated the possible association of PROP taste responsiveness with gustin gene polymorphism rs2274333 (A/G), salivary ionic zinc...
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