A mutation that prevents myosin from overcoming its inhibitions.

doi:10.1085/jgp.202413594

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Article

A mutation that prevents myosin from overcoming its inhibitions.

The Journal of general physiology - 3 Jun 2024

Short Ben

Abstract excerpt

JGP study (Duno-Miranda et al. https://doi.org/10.1085/jgp.202313522) shows that a mutation linked to dilated cardiomyopathy stabilizes β-cardiac myosin in its autoinhibited, super-relaxed state.

Topics

Humans
Mutation
Cardiomyopathy, Dilated
Animals

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