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Article

Expression of senescence-related CD161 promotes extranodal NK/T cell lymphoma by affecting T cell phenotype and cell cycle.

Molecular medicine (Cambridge, Mass.) - 23 Nov 2024

Jin Chengxun, Li Xin, Zhang Chaohe

Abstract excerpt

PURPOSE: The intention of this work is to probe the role of senescence-related gene CD161 in extranodal NK/T cell lymphoma (ENKTL). METHODS: This study used H2O2 to establish three distinct in vitro oxidative stress aging models (NKL, SNT-8, and YT). Western blotting was employed to assess the levels of two iconic aging proteins, MMP1 and P53, and flow cytometry was utilized to investigate cell cycle and the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Neoplastic

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Source

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Identifiers

PMID: 39580409
DOI: 10.1186/s10020-024-00969-7
PMCID: PMC11585959

Genes

CD4
MMP1
CCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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