Article
Clinical and genetic factors involved in Porto-sinusoidal vascular disorder after oxaliplatin exposure.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Oct 2024
Puente A, Fortea J I, Del Pozo C, Serrano M, Alonso-Peña M, Giráldez A, Tellez L, Martinez J, Magaz M, Ibañez L, Garcia J, Llop E, Alvarez-Navascues C, Romero M, Rodriguez E, Arias Loste M T, Antón A, Echavarria V, López C, Albillos A, Hernández-Gea V, Garcia-Pagán J C, Bañares R, Crespo J
Abstract excerpt
BACKGROUND AND AIMS: Oxaliplatin (OX) has been described as a potential etiologic agent for porto-sinusoidal vascular disorder (PSVD). Our aim was to describe the natural history of PSVD due to OX in colon cancer (CRC) and identify risk factors for its development. METHODS: We made a multicenter retrospective case-control (ratio 1:3) study with patients diagnosed of PSVD-OX. Baseline data, end of treatment, years...
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