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Article

Genetic polymorphisms in cyclin H gene are associated with oxaliplatin-induced acute peripheral neuropathy in South Indian digestive tract cancer patients.

Cancer chemotherapy and pharmacology - 1 Sept 2018

Palugulla Sreenivasulu, Devaraju Panneer, Kayal Smita, Narayan Sunil K, Mathaiyan Jayanthi

Abstract excerpt

PURPOSE: Digestive tract cancer patients treated with oxaliplatin are often associated with the development of peripheral neuropathy. The aim of the present study is to identify the influence of single-nucleotide polymorphisms (SNPs) in genes involved in oxaliplatin metabolism, cell cycle control, detoxification or excretion pathways with the development of oxaliplatin-induced acute peripheral neuropathy (acute...

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Source

Identifiers

PMID: 29936608
DOI: 10.1007/s00280-018-3629-1

Genes

CCNH
ABCG2
AGXT
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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