Article
Polymorphic markers associated with severe oxaliplatin-induced, chronic peripheral neuropathy in colon cancer patients.
Cancer - 1 Jun 2012
Won Hong-Hee, Lee Jeeyun, Park Joon Oh, Park Young Suk, Lim Ho Yeong, Kang Won Ki, Kim Jong-Won, Lee Soo-Youn, Park Se Hoon
Abstract excerpt
BACKGROUND: To identify potential genetic markers for severe oxaliplatin-induced chronic peripheral neuropathy (OXCPN), the authors performed a genome-wide association analysis of patients with colon cancer who received oxaliplatin-based chemotherapy. METHODS: This was a prospective study in which DNA was purified in peripheral blood from patients with colon cancer who received oxaliplatin. The primary endpoint...
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