Article
Splenomegaly and Its Associations with Genetic Polymorphisms and Treatment Outcome in Colorectal Cancer Patients Treated with Adjuvant FOLFOX.
Cancer research and treatment - 1 Jul 2016
Kim Mi-Jung, Han Sae-Won, Lee Dae-Won, Cha Yongjun, Lee Kyung-Hun, Kim Tae-Yong, Oh Do-Youn, Kim Se Hyung, Im Seock-Ah, Bang Yung-Jue, Kim Tae-You
Abstract excerpt
PURPOSE: Splenomegaly is a clinical surrogate of oxaliplatin-induced sinusoidal obstruction syndrome (SOS). We investigated development of splenomegaly and its association with treatment outcome and genetic polymorphisms following adjuvant 5-fluorouracil, leucovorin, and oxaliplatin (FOLFOX) in colorectal cancer (CRC) patients. MATERIALS AND METHODS: Splenomegaly was determined by spleen volumetry using computed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.