Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An experimental study to identify the potential role of pharmacogenomics in determining the occurrence of oxaliplatin-induced liver injury.

HPB : the official journal of the International Hepato Pancreato Biliary Association - 1 Aug 2013

Robinson Stuart M, Mann Jelena, Manas Derek M, Mann Derek A, White Steven A

Abstract excerpt

BACKGROUND: Oxaliplatin-based chemotherapy has been linked to the development of sinusoidal obstruction syndrome (SOS), which is detrimental to outcome after liver resection for colorectal liver metastases (CLM). The aim of this study was to determine how the expression of genes involved in the t...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphatases
Share to Cation Transport Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chemical and Drug Induced Liver Injury

Share to Copper-Transporting ATPases

Share to Fluorouracil

Share to Leucovorin

Share to Organoplatinum Compounds

Share to Oxaliplatin

Source

Open in PubMed Open full text

Identifiers

PMID: 23458185
DOI: 10.1111/hpb.12010
PMCID: PMC3731578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23458185-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An experimental study to identify the potential role of pharmacogenomics in determining the occurrence of oxaliplatin-induced liver injury.PMID 23458185Read ↗

Gene Expression Profiling Provides Insights into Pathways of Oxaliplatin-Related Sinusoidal Obstruction Syndrome in HumansSemantic proximity Read ↗

Investigating Genetic Risk to Oxaliplatin-Induced Sinusoidal Obstruction Syndrome in Colorectal Cancer Through Routinely Available Next-Generation Sequencing Data.Semantic proximity Read ↗

Pharmacology of oxaliplatin and the use of pharmacogenomics to individualize therapy.Semantic proximity Read ↗

Oxaliplatin-induced cardiotoxicity in mice is connected to the changes in energy metabolism in the heart tissueSemantic proximity Read ↗

Genetic Characterization to Improve Interpretation and Clinical Management of Hepatotoxicity Caused by Tyrosine Kinase InhibitorsSemantic proximity Read ↗

Peritoneal metastases from colorectal cancer belong to Consensus Molecular Subtype 4 and are sensitised to oxaliplatin by inhibiting reducing capacitySemantic proximity Read ↗

Functional Genomics Reveals Diverse Cellular Processes That Modulate Tumor Cell Response to OxaliplatinSemantic proximity Read ↗

Clinical and genetic factors involved in Porto-sinusoidal vascular disorder after oxaliplatin exposure.Semantic proximity Read ↗

The cellular pharmacology of oxaliplatin resistanceSemantic proximity Read ↗

Glutathione S-transferase M1-null genotype as risk factor for SOS in oxaliplatin-treated patients with metastatic colorectal cancer.Semantic proximity Read ↗

Oxaliplatin-induced haematological toxicity and splenomegaly in mice.Semantic proximity Read ↗

Genetic polymorphisms in cyclin H gene are associated with oxaliplatin-induced acute peripheral neuropathy in South Indian digestive tract cancer patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.