Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dissecting the genetic and causal relationship between sleep-related traits and common brain disorders.

Sleep medicine - 1 Jul 2024

Xue Baiqiang, Jian Xuemin, Peng Lixia, Wu Chuanhong, Fahira Aamir, Syed Ali Alamdar Shah, Xia Disong, Wang Baokun, Niu Mingming, Jiang Yajie, Ding Yonghe, Gao Chengwen, Zhao Xiangzhong, Zhang Qian, Shi Yongyong, Li Zhiqiang

Abstract excerpt

BACKGROUND: There is a profound connection between abnormal sleep patterns and brain disorders, suggesting a shared influential association. However, the shared genetic basis and potential causal relationships between sleep-related traits and brain disorders are yet to be fully elucidated. METHODS: Utilizing linkage disequilibrium score regression (LDSC) and bidirectional two-sample univariable Mendelian...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Diseases
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Linkage Disequilibrium

Share to Mendelian Randomization Analysis

Share to Sleep Wake Disorders

Source

Identifiers

PMID: 38703603
DOI: 10.1016/j.sleep.2024.04.032

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dissecting the genetic and causal relationship between sleep-related traits and common brain disorders.PMID 38703603Read ↗

Shared Genetic Links Between Sleep, Neurodevelopmental and Neuropsychiatric Conditions: A Genome-Wide and Pathway-Based Polygenic Score Analysis.Semantic proximity Read ↗

Sleep-related traits and attention-deficit/hyperactivity disorder comorbidity: Shared genetic risk factors, molecular mechanisms, and causal effects.Semantic proximity Read ↗

From single nucleotide variations to genes: identifying the genetic links between sleep and psychiatric disorders.Semantic proximity Read ↗

Causal links between major depressive disorder and insomnia: A Mendelian randomisation study.Semantic proximity Read ↗

Sleep deficits and cannabis use behaviors: an analysis of shared genetics using linkage disequilibrium score regression and polygenic risk predictionSemantic proximity Read ↗

Characterizing the Genetic Overlap Between Psychiatric Disorders and Sleep-Related Phenotypes.Semantic proximity Read ↗

Shared genetic liability and causal effects between major depressive disorder and insomnia.Semantic proximity Read ↗

Neurodevelopment as a shared genetic etiology linking sleep-related phenotypes and psychiatric disorders: a genome-wide pleiotropic analysis.Semantic proximity Read ↗

Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits.Semantic proximity Read ↗

Investigating the causal role of sleep disorders in anorexia nervosa and obsessive-compulsive disorder: a bidirectional Mendelian randomization study.Semantic proximity Read ↗

The relationship between alcohol- and sleep-related traits: Results from polygenic risk score and Mendelian randomization analyses.Semantic proximity Read ↗

The Causal Effects of Insomnia on Bipolar Disorder, Depression, and Schizophrenia: A Two-Sample Mendelian Randomization StudySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.