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Article

Causal links between major depressive disorder and insomnia: A Mendelian randomisation study.

Gene - 5 Feb 2021

Cai Lei, Bao Yiran, Fu Xiaoqian, Cao Hongbao, Baranova Ancha, Zhang Xiangrong, Sun Jing, Zhang Fuquan

Abstract excerpt

Both Major depressive disorder (MDD) and insomnia are two common mental disorders. However, the inherent and comprehensive genetic factors causing the links between MDD and insomnia are unclear yet. Here, based on GWAS results for each disorder, we used linkage disequilibrium (LD) score regression analysis and a multi-single nucleotide polymorphism (SNP) Mendelian randomization (MR) analysis to test the genetic...

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Source

Identifiers

PMID: 33122081
DOI: 10.1016/j.gene.2020.145271

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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