Investigating the causal role of sleep disorders in anorexia nervosa and obsessive-compulsive disorder: a bidirectional Mendelian randomization study.

Abstract excerpt

BACKGROUND: Whether common sleep phenotypes causally influence anorexia nervosa (AN) or obsessive-compulsive disorder (OCD) is unclear; we used Mendelian randomization (MR) to test effects of daytime sleepiness (DS), insomnia, and sleep apnea (SA) on AN and OCD, and the reverse direction. METHODS: We conducted bidirectional two-sample MR using genome-wide association studies (GWAS) of DS (N = 452,071), insomnia...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Anorexia Nervosa
• Share to Genetic Predisposition to Disease