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Article

Characterizing the Genetic Overlap Between Psychiatric Disorders and Sleep-Related Phenotypes.

Biological psychiatry - 1 Nov 2021

O'Connell Kevin S, Frei Oleksandr, Bahrami Shahram, Smeland Olav B, Bettella Francesco, Cheng Weiqiu, Chu Yunhan, Hindley Guy, Lin Aihua, Shadrin Alexey, Barrett Elizabeth Ann, Lagerberg Trine Vik, Steen Nils Eiel, Dale Anders M, Djurovic Srdjan, Andreassen Ole A

Abstract excerpt

BACKGROUND: A range of sleep disturbances are commonly experienced by patients with psychiatric disorders, and genome-wide genetic analyses have shown some significant genetic correlations between these traits. Here, we applied novel statistical genetic methodologies to better characterize the potential shared genetic architecture between sleep-related phenotypes and psychiatric disorders. METHODS: Using the...

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Identifiers

PMID: 34482950
DOI: 10.1016/j.biopsych.2021.07.007

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