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Article

The Interplay Between Sleep and Mental Health: A Genetic Perspective.

Biological psychiatry - 1 Dec 2025

Kozhemiako Nataliia, Mita Carol, Panagiotaropoulou Georgia M, Lewis Katie J S, Sofer Tamar, Purcell Shaun M

Abstract excerpt

Although many facets of sleep, including subjective, behavioral, and neurophysiological features, are closely linked with psychiatric disorders, the natures of these relationships are generally unclear. A given alteration in sleep could reflect a cause (that may mediate genetic risk), consequence, symptom, trigger, epiphenomenon due to shared determinants, or some combination of these. In principle, genetic...

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Topics

Humans
Sleep
Mental Disorders
Genome-Wide Association Study
Sleep Wake Disorders
Mental Health

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genetic Predisposition to Disease

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Identifiers

PMID: 40618946
DOI: 10.1016/j.biopsych.2025.06.024
PMCID: PMC7619434

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