Article
From single nucleotide variations to genes: identifying the genetic links between sleep and psychiatric disorders.
Sleep - 13 Jan 2025
Jia Ningning, Zhu Zhenhua, Liu Yane, Yin Xuyuan, Man Lijuan, Hou Wenlong, Zhang Huiping, Yu Qiong, Hui Li
Abstract excerpt
STUDY OBJECTIVES: Sleep disorders and psychiatric disorders frequently coexist and interact, yet the shared genetic basis linking these two domains remains poorly understood. METHODS: We investigated the genetic correlation and overlap between seven sleep/circadian traits and three psychiatric disorders at the level of genome-wide association studies (GWAS), utilizing LDSC, HDL, and GPA. To identify potential...
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