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Article

Ecological and evolutionary mechanisms driving within-patient emergence of antimicrobial resistance.

Nature reviews. Microbiology - 1 Oct 2024

Shepherd Matthew J, Fu Taoran, Harrington Niamh E, Kottara Anastasia, Cagney Kendall, Chalmers James D, Paterson Steve, Fothergill Joanne L, Brockhurst Michael A

Abstract excerpt

The ecological and evolutionary mechanisms of antimicrobial resistance (AMR) emergence within patients and how these vary across bacterial infections are poorly understood. Increasingly widespread use of pathogen genome sequencing in the clinic enables a deeper understanding of these processes. In this Review, we explore the clinical evidence to support four major mechanisms of within-patient AMR emergence in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38689039
DOI: 10.1038/s41579-024-01041-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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