Article
Antimicrobial resistance: its emergence and transmission.
Animal health research reviews - 1 Dec 2008
Boerlin Patrick, Reid-Smith Richard J
Abstract excerpt
New concepts have emerged in the past few years that help us to better understand the emergence and spread of antimicrobial resistance (AMR). These include, among others, the discovery of the mutator state and the concept of mutant selection window for resistances emerging primarily through mutations in existing genes. Our understanding of horizontal gene transfer has also evolved significantly in the past few...
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