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Article

A Cell Specific Effect of MBOAT7 MAFLD-risk Variant on Immune Cells.

Frontiers in bioscience (Landmark edition) - 11 Apr 2024

Pan Ziyan, Alharthi Jawaher, Bayoumi Ali, George Jacob, Eslam Mohammed

Abstract excerpt

BACKGROUND: Disease risk variants are likely to affect gene expression in a context- and cell-type specific manner. The membrane bound O-acyltransferase domain containing 7 (MBOAT7) rs8736 metabolic-dysfunction-associated fatty liver disease (MAFLD)-risk variant was recently reported to be a negative regulator of toll-like receptors (TLRs) signalling in macrophages. Whether this effect is generic or cell-type...

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Identifiers

PMID: 38682204
DOI: 10.31083/j.fbl2904148

Genes

MBOAT7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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