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Article

Comprehensive genomic profiling of pulmonary spindle cell carcinoma using tissue and plasma samples: insights from a real-world cohort analysis.

The journal of pathology. Clinical research - 1 May 2024

Sun Yi, Qin Shilei, Wang Song, Pang Jiaohui, Ou Qiuxiang, Liang Weiquan, Zhong Hai

Abstract excerpt

Pulmonary spindle cell carcinoma (PSCC) is a rare and aggressive non-small cell lung cancer (NSCLC) subtype with a dismal prognosis. The molecular characteristics of PSCC are largely unknown due to its rarity, which limits the diagnosis and treatment of this historically poorly characterized malignancy. We present comprehensive genomic profiling results of baseline tumor samples from 22 patients histologically...

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Source

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Identifiers

PMID: 38661052
DOI: 10.1002/2056-4538.12375
PMCID: PMC11044156

Genes

ALK
KRAS
MET
ARID2
CDKN2A
EGFR
ERBB2
FOXL2
LRP1B
ROS1
TERT
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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