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Article

Genomic Landscape of Pulmonary Sarcomatoid Carcinoma.

Cancer research and treatment - 1 Apr 2024

Kwon Hyun Jung, Lee Sejoon, Han Yeon Bi, Lee Jeonghyo, Kwon Soohyeon, Kim Hyojin, Chung Jin-Haeng

Abstract excerpt

PURPOSE: Pulmonary sarcomatoid carcinoma (PSC) is a rare aggressive subtype of non-small cell lung cancer (NSCLC) with limited therapeutic strategies. We attempted to elucidate the evolutionary trajectories of PSC using multiregional and longitudinal tumor samples. MATERIALS AND METHODS: A total of 31 patients were enrolled in this study and 11 longitudinal samples were available from them. Using whole exome...

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Identifiers

PMID: 37973906
DOI: 10.4143/crt.2023.764
PMCID: PMC11016656

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