Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deep Sequencing Analysis Reveals That KRAS Mutation Is a Marker of Poor Prognosis in Patients with Pulmonary Sarcomatoid Carcinoma.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Aug 2016

Lococo Filippo, Gandolfi Greta, Rossi Giulio, Pinto Carmine, Rapicetta Cristian, Cavazza Alberto, Cesario Alfredo, Galeone Carla, Paci Massimiliano, Ciarrocchi Alessia

Abstract excerpt

INTRODUCTION: Pulmonary sarcomatoid carcinoma (PSC) is a rare and aggressive subset of non-small cell lung cancer with limited treatment options. The molecular characterization of PSC has been strongly hampered by the relative rarity of these tumors. However, understanding the molecular and genetic bases of PSCs is critical to pave the way to new treatment options. In this work, we aimed to explore the complexity...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to ErbB Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, p53

Share to High-Throughput Nucleotide Sequencing

Share to Lung Neoplasms

Share to Proto-Oncogene Proteins c-met

Share to Proto-Oncogene Proteins p21(ras)

Share to Sarcoma

Source

Identifiers

PMID: 27156442
DOI: 10.1016/j.jtho.2016.04.020

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deep Sequencing Analysis Reveals That KRAS Mutation Is a Marker of Poor Prognosis in Patients with Pulmonary Sarcomatoid Carcinoma.PMID 27156442Read ↗

Analysis of molecular pathologic and clinical features of 36 patients with pulmonary sarcomatoid carcinoma.Semantic proximity Read ↗

Pulmonary Sarcomatoid Carcinomas Commonly Harbor Either Potentially Targetable Genomic Alterations or High Tumor Mutational Burden as Observed by Comprehensive Genomic Profiling.Semantic proximity Read ↗

KRAS mutation is predictive of outcome in patients with pulmonary sarcomatoid carcinoma.Semantic proximity Read ↗

Genetic characterisation of sarcomatoid carcinomas reveals multiple novel actionable mutations and identifies KRAS mutation as a biomarker of poor prognosis.Semantic proximity Read ↗

Analysis of molecular pathologic and clinical features of 36 patients with pulmonary sarcomatoid carcinomaSemantic proximity Read ↗

Integrated molecular characterization reveals potential therapeutic strategies for pulmonary sarcomatoid carcinoma.Semantic proximity Read ↗

Comprehensive genomic profiling of pulmonary spindle cell carcinoma using tissue and plasma samples: insights from a real-world cohort analysis.Semantic proximity Read ↗

Integrative genomic and transcriptomic profiling of pulmonary sarcomatoid carcinoma identifies molecular subtypes associated with distinct immune features and clinical outcomesSemantic proximity Read ↗

High-throughput somatic mutation profiling in pulmonary sarcomatoid carcinomas using the LungCarta™ Panel: exploring therapeutic targets.Semantic proximity Read ↗

Genomic Landscape of Pulmonary Sarcomatoid Carcinoma.Semantic proximity Read ↗

Whole transcriptome targeted gene quantification provides new insights on pulmonary sarcomatoid carcinomasSemantic proximity Read ↗

Characterization of KRAS Mutation Subtypes in Non-small Cell Lung Cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.