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Article

Mendelian randomization analysis identifies druggable genes and drugs repurposing for chronic obstructive pulmonary disease.

Frontiers in cellular and infection microbiology - 1 Jan 2024

Wang Zihui, Li Shaoqiang, Cai Guannan, Gao Yuan, Yang Huajing, Li Yun, Liang Juncheng, Zhang Shiyu, Hu Jieying, Zheng Jinping

Abstract excerpt

Background: Chronic obstructive pulmonary disease (COPD) is a prevalent condition that significantly impacts public health. Unfortunately, there are few effective treatment options available. Mendelian randomization (MR) has been utilized to repurpose existing drugs and identify new therapeutic targets. The objective of this study is to identify novel therapeutic targets for COPD. Methods: Cis-expression...

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Share to ERBB3 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

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Share to Polymorphism, Single Nucleotide

Share to Pulmonary Disease, Chronic Obstructive

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Source

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Identifiers

PMID: 38660492
DOI: 10.3389/fcimb.2024.1386506
PMCID: PMC11039854

Genes

ERBB3
MMP15
PSMA4
APH1A
GP9
LMCD1
MRC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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