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Article

Prioritization of therapeutic targets for cancers using integrative multi-omics analysis.

Human genomics - 24 Apr 2024

Jin Xin, Mei Yunyun, Yang Puyu, Huang Runze, Zhang Haifeng, Wu Yibin, Wang Miao, He Xigan, Jiang Ziting, Zhu Weiping, Wang Lu

Abstract excerpt

BACKGROUND: The integration of transcriptomic, proteomic, druggable genetic and metabolomic association studies facilitated a comprehensive investigation of molecular features and shared pathways for cancers' development and progression. METHODS: Comprehensive approaches consisting of transcriptome-wide association studies (TWAS), proteome-wide association studies (PWAS), summary-data-based Mendelian...

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Identifiers

PMID: 38659038
DOI: 10.1186/s40246-024-00571-2
PMCID: PMC11040978

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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