Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Machine Learning Identifies Pan-Cancer Landscape of Nrf2 Oxidative Stress Response Pathway-Related Genes.

Oxidative medicine and cellular longevity - 1 Jan 2022

Li Na, Zhan Xianquan

Abstract excerpt

BACKGROUND: Oxidative stress produced a large amount of reactive oxygen species (ROS), which played a pivotal role in balanced ability and determining cell fate. The activated Nrf2 signaling pathway that responds to the excessive ROS regulated the expressions of antiapoptotic proteins, antioxidative enzymes, drug transporters, and detoxifying factors. METHODS: The Nrf2 signaling pathway-related genes that had a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Machine Learning
Share to Mutation Rate
Share to NF-E2-Related Factor 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Oxidative Stress

Share to Reactive Oxygen Species

Share to Survival Rate

Share to Transcriptome

Share to Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 35242279
DOI: 10.1155/2022/8450087
PMCID: PMC8886747

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Machine Learning Identifies Pan-Cancer Landscape of Nrf2 Oxidative Stress Response Pathway-Related Genes.PMID 35242279Read ↗

Establishment and external verification of an oxidative stress-related gene signature to predict clinical outcomes and therapeutic responses of colorectal cancerSemantic proximity Read ↗

A core NRF2 gene set defined through comprehensive transcriptomic analysis predicts selective drug resistance and poor multi-cancer prognosisSemantic proximity Read ↗

Comprehensive analysis of breast cancer oxidative stress related gene signature: a combination of bulk and single-cell RNA sequencing analysis.Semantic proximity Read ↗

Oxidative Stress Gene Expression Profile Correlates with Cancer Patient Poor Prognosis: Identification of Crucial Pathways Might Select Novel Therapeutic ApproachesSemantic proximity Read ↗

Multi-Omics Analysis of Cancer Cell Lines with High/Low Ferroptosis Scores and Development of a Ferroptosis-Related Model for Multiple Cancer TypesSemantic proximity Read ↗

Molecular mechanisms and systemic targeting of NRF2 dysregulation in cancer.Semantic proximity Read ↗

An oxidative stress response gene model for the prediction of prognosis and therapeutic responses in hepatocellular carcinomaSemantic proximity Read ↗

Nrf2, the master redox switch: the Achilles' heel of ovarian cancer?Semantic proximity Read ↗

Nuclear Factor Erythroid 2-Related Factor 2 in Regulating Cancer Metabolism.Semantic proximity Read ↗

Development and validation of endoplasmic reticulum stress-related LncRNA signature as a novel prognosis model for LUADSemantic proximity Read ↗

Exploration of oxidative stress-related hub genes in idiopathic pulmonary fibrosis by integrating bioinformatics analysisSemantic proximity Read ↗

Identification of the Signature Genes and Network of Reactive Oxygen Species Related Genes and DNA Repair Genes in Lung AdenocarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.