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HLA-DRB1 and HLA-DQB1 genes in patients diagnosed with systemic lupus erythematosus in Guatemala.

Human immunology - 1 May 2024

Barrios-Menéndez Juan C, Carías-Alvarado César Camilo, Cayax Lilian Isabel, López-Hun Francisco, Santizo Adolfo, Herrera Maynor A, Hernández-Zaragoza Diana Iraíz, Escobar-Castro Karla

Abstract excerpt

Systemic lupus erythematosus (SLE) is an autoimmune disorder that impacts connective tissue and can affect various organs and systems within the body. One important aspect of this disease is the role of the human leukocyte antigen (HLA) system, a protein complex that plays a role in the immune response. Specifically, the HLA-DRB1 and HLA-DQB1 genes have been implicated in the development of SLE. In order to...

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PMID: 38653667
DOI: 10.1016/j.humimm.2024.110803

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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