Article
Association of class II HLA alleles with susceptibility to develop immune-mediated diseases in Paraguayan patients.
International journal of immunogenetics - 1 Feb 2023
Acosta-Colman Isabel, Cabrera-Villalba Sonia, Ayala-Lugo Ana, Jolly Valerie, Vazquez Marcos, Morel Zoilo, Langjahr Patricia, Duarte Margarita, Zarate Ruth, Acosta Maria Eugenia, Avila-Pedretti Gabriela, Julià Antonio, Martinez María Teresa, Marsal Sara
Abstract excerpt
Genetic and nongenetic factors are involved in the pathogenesis of immune-mediated inflammatory diseases (IMIDs). The best-known genetic factor for susceptibility to IMIDs is the human leukocyte antigen (HLA). The aim of the present study was to evaluate the association of HLA class II genes with the risk of systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and systemic sclerosis (SSc) in the...
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