Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Correlation analysis of serum TLR4 protein levels and TLR4 gene polymorphisms in gouty arthritis patients.

PloS one - 1 Jan 2024

Liu Lu, He Shuang, Jia Lin, Yao Hua, Zhou Dan, Guo Xiaobin, Miao Lei

Abstract excerpt

OBJECTIVE: The Toll-like receptor (TLR) 4-mediated nuclear factor kappa B (NF-κB) signaling pathway regulates the production of inflammatory factors and plays a key role in the pathogenesis of gouty arthritis. The aim of the present study was to investigate the link among TLR4 gene polymorphisms at various loci, protein expression, and gouty arthritis susceptibility. METHODS: Between 2016 and 2021, a case-control...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Case-Control Studies
Share to TLR4 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Polymorphism, Single Nucleotide

Share to Toll-Like Receptor 4

Source

Open in PubMed Open full text

Identifiers

PMID: 38652726
DOI: 10.1371/journal.pone.0300582
PMCID: PMC11037531

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Correlation analysis of serum TLR4 protein levels and TLR4 gene polymorphisms in gouty arthritis patients.PMID 38652726Read ↗

Association of TLR4 Gene rs2149356 polymorphism with primary gouty arthritis in a case-control study.Semantic proximity Read ↗

NLRP3 Susceptible Gene Polymorphisms in Patients with Primary Gouty Arthritis and Hyperuricemia.Semantic proximity Read ↗

Toll-Like receptor 4 (TLR4) polymorphism rs2149356 and risk of gout in a Spanish cohort.Semantic proximity Read ↗

Associations Between the NLRP3 and IL-1β Gene Polymorphisms and Gout SusceptibilitySemantic proximity Read ↗

Global research trends and priorities in the link between Toll-like receptors and rheumatoid arthritis: a bibliometric analysis from 2003 to 2023Semantic proximity Read ↗

Associations of toll-like receptor 4 and 2 gene polymorphisms with susceptibility to ankylosing spondylitis: A meta-analysis.Semantic proximity Read ↗

The Genetic Association Between TLR-1, -2, -4, and -6 Gene Polymorphisms and Rheumatoid Arthritis Susceptibility in a Chinese Han Population.Semantic proximity Read ↗

What do we know about Toll-Like Receptors Involvement in Gout Arthritis?Semantic proximity Read ↗

Association of Toll-like Receptor 4 Rs7873784 G/C Polymorphism with Rheumatoid Arthritis Risk in a Chinese Population.Semantic proximity Read ↗

The Genetic Immune Basis of Gout: Identification, Functional Characterization, and Therapeutic ImplicationsSemantic proximity Read ↗

Association of integrin-β2 polymorphism and expression with the risk of rheumatoid arthritis and osteoarthritis in Egyptian patients.Semantic proximity Read ↗

Associations of toll-like receptor (TLR)-4 single nucleotide polymorphisms and rheumatoid arthritis disease progression: an observational cohort study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.