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Article

Carrageenan maintains the contractile phenotype of vascular smooth muscle cells by increasing macromolecular crowding in vitro.

European journal of medical research - 22 Apr 2024

Liu Qing, Jiang Hong-Jing, Wu Yin-Di, Li Jian-Dong, Sun Xu-Heng, Xiao Cong, Xu Jian-Yi, Lin Zhan-Yi

Abstract excerpt

BACKGROUND: The contractile phenotype of vascular smooth muscle cells (VSMCs) results in good diastolic and contractile capacities, and its altered function is the main pathophysiological basis for diseases such as hypertension. VSMCs exist as a synthetic phenotype in vitro, making it challenging to maintain a contractile phenotype for research. It is widely recognized that the common medium in vitro is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38650027
DOI: 10.1186/s40001-024-01843-2
PMCID: PMC11036678

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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