Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

C/ EBPβ : A transcription factor associated with the irreversible progression of Alzheimer's disease

1 Apr 2024

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disorder distinguished by a swift cognitive deterioration accompanied by distinctive pathological hallmarks such as extracellular Aβ (β-amyloid) peptides, neuronal neurofibrillary tangles (NFTs), sustained neuroinflammation, and synaptic degeneration. The elevated frequency of AD cases and its proclivity to manifest at a younger age present a pressing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Genetics, Aging, and Longevity in Model Organisms
Share to Ion Channels and Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38644578
DOI: 10.1111/cns.14721

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

C/ EBPβ : A transcription factor associated with the irreversible progression of Alzheimer's diseasePMID 38644578Read ↗

C/EBPβ regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer’s diseaseSemantic proximity Read ↗

C/EBPβ is a key transcription factor for APOE and preferentially mediates ApoE4 expression in Alzheimer’s diseaseSemantic proximity Read ↗

TFEB in Alzheimer's disease: From molecular mechanisms to therapeutic implicationsSemantic proximity Read ↗

Neuronal C/EBPβ/AEP pathway shortens life span via selective GABAnergic neuronal degeneration by FOXO repressionSemantic proximity Read ↗

Neuronal ApoE4 stimulates C/EBPβ activation, promoting Alzheimer’s disease pathology in a mouse modelSemantic proximity Read ↗

Novel Insight into Functions of Transcription Factor EB (TFEB) in Alzheimer’s Disease and Parkinson’s DiseaseSemantic proximity Read ↗

Amyloid-β₄₂ activates the expression of BACE1 through the JNK pathway.Semantic proximity Read ↗

IRE1 signaling exacerbates Alzheimer’s disease pathogenesisSemantic proximity Read ↗

Regulation of β‐site APP‐cleaving enzyme 1 gene expression and its role in Alzheimer’s DiseaseSemantic proximity Read ↗

The unfolded protein response transcription factor XBP1s ameliorates Alzheimer’s disease by improving synaptic function and proteostasisSemantic proximity Read ↗

Closing in on the amyloid cascade: recent insights into the cell biology of Alzheimer's disease.Semantic proximity Read ↗

The regulatory mechanism and therapeutic potential of transcription factor <scp>EB</scp> in neurodegenerative diseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.