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Mitochondria function in cytoplasmic FeS protein biogenesis

17 Apr 2024

Abstract excerpt

Iron‑sulfur (FeS) clusters are cofactors of numerous proteins involved in various essential functions including cellular respiration, protein translation, DNA synthesis and repair, ribosome maturation, anti-viral responses, and isopropylmalate isomerase activity. Novel FeS cluster proteins are still being discovered due to the widespread use of cryogenic electron microscopy (cryo-EM) and elegant genetic screens...

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PMID: 38641180
DOI: 10.1016/j.bbamcr.2024.119733

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