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Article

Postpartum Breast Cancer and Survival in Women With Germline BRCA Pathogenic Variants.

JAMA network open - 1 Apr 2024

Zhang Zhenzhen, Ye Shangyuan, Bernhardt Sarah M, Nelson Heidi D, Velie Ellen M, Borges Virginia F, Woodward Emma R, Evans D Gareth R, Schedin Pepper J

Abstract excerpt

Importance: In young-onset breast cancer (YOBC), a diagnosis within 5 to 10 years of childbirth is associated with increased mortality. Women with germline BRCA1/2 pathogenic variants (PVs) are more likely to be diagnosed with BC at younger ages, but the impact of childbirth on mortality is unknown. Objective: To determine whether time between most recent childbirth and BC diagnosis is associated with mortality...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38639936
DOI: 10.1001/jamanetworkopen.2024.7421
PMCID: PMC11031688

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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