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Adaptation of the Mycobacterium tuberculosis transcriptome to biofilm growth

18 Apr 2024

Abstract excerpt

Mycobacterium tuberculosis (M. tb), the causative agent of tuberculosis (TB), is a leading global cause of death from infectious disease. Biofilms are increasingly recognized as a relevant growth form during M. tb infection and may impede treatment by enabling bacterial drug and immune tolerance. M. tb has a complicated regulatory network that has been well-characterized for many relevant disease states,...

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PMID: 38635841
DOI: 10.1371/journal.ppat.1012124

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