Article
Relaxed selection drives a noisy noncoding transcriptome in members of the Mycobacterium tuberculosis complex.
mBio - 5 Aug 2014
Dinan Adam M, Tong Pin, Lohan Amanda J, Conlon Kevin M, Miranda-CasoLuengo Aleksandra A, Malone Kerri M, Gordon Stephen V, Loftus Brendan J
Abstract excerpt
Related species are often used to understand the molecular underpinning of virulence through examination of a shared set of biological features attributable to a core genome of orthologous genes. An important but insufficiently studied issue, however, is the extent to which the regulatory architectures are similarly conserved. A small number of studies have compared the primary transcriptomes of different...
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