Article
Rapid adaptation of a complex trait during experimental evolution of Mycobacterium tuberculosis
16 May 2022
Abstract excerpt
Tuberculosis (TB), caused by Mycobacterium tuberculosis ( M. tb ), is a leading cause of death due to infectious disease. TB is not traditionally associated with biofilms, but M. tb biofilms are linked with drug and immune tolerance and there is increasing recognition of their contribution to the recalcitrance of TB infections. Here, we used M. tb experimental evolution to investigate this complex phenotype and...
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