Article
The complexity of human leukocyte antigen (HLA)-DQ antibodies and its effect on virtual crossmatching.
Transplantation - 27 Nov 2010
Tambur Anat R, Leventhal Joseph R, Friedewald John J, Ramon Daniel S
Abstract excerpt
BACKGROUND: We previously reported that in patients possessing human leukocyte antigen (HLA)-DQ-directed antibodies, the target molecule may include the patient's own DQβ chain if it is paired with non-self-DQα chain, thus forming a different DQ target. Herein, we sought to assess the breadth of...
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