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Article

ELK3 destabilization by speckle-type POZ protein suppresses prostate cancer progression and docetaxel resistance.

Cell death & disease - 17 Apr 2024

Lee Cheol-Jung, Lee Heejung, Kim Seo Ree, Nam Soo-Bin, Lee Ga-Eun, Yang Kyeong Eun, Lee Guk Jin, Chun Sang Hoon, Kang Han Chang, Lee Joo Young, Lee Hye Suk, Cho Sung-Jun, Cho Yong-Yeon

Abstract excerpt

Accumulating evidence demonstrates that the activity regulation of ELK3, a member of the E26 transformation-specific oncogene family, is critical to regulating cell proliferation, migration, and survival in human cancers. However, the molecular mechanisms of how ELK3 induces chemoresistance in prostate cancer (PCa) have not been elucidated. In this study, we found that SPOP and ELK3 are an interacting partner....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38632244
DOI: 10.1038/s41419-024-06647-0
PMCID: PMC11024157

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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ELK3 destabilization by speckle-type POZ protein suppresses prostate cancer progression and docetaxel resistance.PMID 38632244Read ↗

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